Haemostatic gene polymorphisms in venous and arterial thrombosis.

  title={Haemostatic gene polymorphisms in venous and arterial thrombosis.},
  author={David A Lane and Luigina R Mollica},
  journal={Pathophysiology of haemostasis and thrombosis},
  volume={32 5-6},
Haemostatic gene polymorphisms are potential risk factors for thrombosis. Considerable attention has been focussed on identifying risk alleles. Progress has undoubtedly been made in venous thrombosis. Factor V Leiden and the prothrombin G20210A substitution are now established risk factors, and a number of other polymorphisms are candidates. The initial promise that genetic risk factors might contribute appreciably to an explanation of the development of arterial thrombotic disorders has… CONTINUE READING


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