Haemopoietic cell transplantation in children with juvenile myelomonocytic leukaemia.

@article{Macmillan1998HaemopoieticCT,
  title={Haemopoietic cell transplantation in children with juvenile myelomonocytic leukaemia.},
  author={Margaret L Macmillan and Stella M. Davies and P J Orchard and Norma K. C. Ramsay and John E Wagner},
  journal={British journal of haematology},
  year={1998},
  volume={103 2},
  pages={552-8}
}
Seven children, 11 months to 5.9 years of age, with juvenile myelomonocytic leukaemia (JMML) underwent allogeneic haemopoietic cell transplantation (HCT) using related or unrelated donor bone marrow or umbilical cord blood. All patients had active disease at time of transplant despite chemotherapy in five patients and chemotherapy and splenectomy in one patient prior to HCT conditioning. All patients received cyclophosphamide and TBI, with the addition of busulphan in two cases. Engraftment was… CONTINUE READING
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