Haemopoietic cell kinetics in humans treated with rGM-CSF.

@article{Lord1992HaemopoieticCK,
  title={Haemopoietic cell kinetics in humans treated with rGM-CSF.},
  author={Brian Iles Lord and Howard Gurney and Jiwon Chang and Nicholas Thatcher and Derek Crowther and T. Michael Dexter},
  journal={International journal of cancer},
  year={1992},
  volume={50 1},
  pages={
          26-31
        }
}
We have investigated the kinetics of myeloid cell proliferation in the marrow of patients with small-cell lung cancer and treated with 10 daily subcutaneous injections of granulocyte/macrophage colony-stimulating factor (GM-CSF). Bone marrow, obtained before and during treatment with the growth factor, was labelled in vitro with tritiated thymidine (3H-TdR). A 3rd bone-marrow sample was obtained 1 hr following an intravenous injection of 3H-TdR. Subsequent daily blood samples were also… CONTINUE READING
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