Haemopoiesis in human fetal and embryonic liver

@article{Timens2005HaemopoiesisIH,
  title={Haemopoiesis in human fetal and embryonic liver},
  author={Wim Timens and Willem A. Kamps and Thea Rozeboom-Uiterwijk and Sibrand Poppema Frcp},
  journal={Virchows Archiv A},
  year={2005},
  volume={416},
  pages={429-436}
}
Paraffin embedded tissue reactive monoclonal antibodies were used to study human embryonal and fetal haemopoiesis, combining optimal morphology with immunohistological determination of haemopoietic cell subtypes and their microenvironment. Seven embryonal and twelve fetal liver specimens were studied, having been fixed in B5-fixative and embedded in paraffin. The different haemopoietic lineages each showed their own immunophenotype and distribution; intercellular and microenvironmental… 
Histochemical in situ identification of bovine embryonic blood cells reveals differences to the adult haematopoietic system and suggests a close relationship between haematopoietic stem cells and primordial germ cells
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Cryostat sections of bovine embryos of exactly known age were treated with a wide range of antibodies directed against cell surface antigens or lineage-specific factors in order to demonstrate different types of fetal blood cells and their precursors.
Immunocytochemical observations on macrophage populations in normal fetal and adult human liver
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It is concluded that the population of human liver macrophages is heterogeneous from an early stage of fetal development and that this heterogeneity extends into adult life.

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