Haemophilus influenzae: surface antigens and aspects of virulence.

  • Ronald Munson
  • Published 1990 in
    Canadian journal of veterinary research = Revue…

Abstract

Haemophilus influenzae type b is a major cause of bacterial meningitis and other invasive diseases in children under four years of age. One surface antigen, the type b capsular polysaccharide, polyribosylribitol phosphate (PRP), is a primary virulence factor of the organism. Antibody directed against PRP is protective; however, the purified polysaccharide… (More)

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