Haemoglobin scavenger receptor: function in relation to disease.

@article{ZuwaaJagieo2006HaemoglobinSR,
  title={Haemoglobin scavenger receptor: function in relation to disease.},
  author={Jolanta Zuwała-Jagiełło},
  journal={Acta biochimica Polonica},
  year={2006},
  volume={53 2},
  pages={257-68}
}
Highly efficient systems remove the toxic and proinflammatory haemoglobin from the circulation and local sites of tissue damage. Macrophages are major haemoglobin-clearing cells; CD163 was recently recognized as the specific haemoglobin scavenger receptor (HbSR). It is tightly involved in both physiological as well as pathophysiological processes, such as cytoprotection and inflammation. Haemoglobin functions as a double-edged sword. In moderate quantities and bound to haptoglobin, it forms a… CONTINUE READING

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