Haemoglobin scavenger receptor: function in relation to disease.

  title={Haemoglobin scavenger receptor: function in relation to disease.},
  author={Jolanta Zuwała-Jagiełło},
  journal={Acta biochimica Polonica},
  volume={53 2},
Highly efficient systems remove the toxic and proinflammatory haemoglobin from the circulation and local sites of tissue damage. Macrophages are major haemoglobin-clearing cells; CD163 was recently recognized as the specific haemoglobin scavenger receptor (HbSR). It is tightly involved in both physiological as well as pathophysiological processes, such as cytoprotection and inflammation. Haemoglobin functions as a double-edged sword. In moderate quantities and bound to haptoglobin, it forms a… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 102 references

CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.

The international journal of biochemistry & cell biology • 2002
View 5 Excerpts
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Identification of the haemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma

HJ Möller, NA Peterslund, JH Graversen, SK Moestrup
Blood • 2002
View 5 Excerpts
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The haem-haem oxygenase system: a molecular switch in wound healing

FA Wagener, HE Van Beurden, JW Von Den Hoff, GJ Adema, CG Figdor
Blood • 2003
View 6 Excerpts
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Cardiovascular diabetology • 2002
View 1 Excerpt
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