Haemoglobin inhibits the development of infective promastigotes and chitinase secretion in Leishmania major cultures.

@article{Schlein1994HaemoglobinIT,
  title={Haemoglobin inhibits the development of infective promastigotes and chitinase secretion in Leishmania major cultures.},
  author={Yosef Schlein and Raymond Leonard Jacobson},
  journal={Parasitology},
  year={1994},
  volume={109 ( Pt 1)},
  pages={23-8}
}
Haemoglobin or blood in the growth medium of Leishmania major inhibited the formation of infective promastigotes and the secretion of chitinases. Inoculation of mice with stationary-phase parasites from control medium caused infections in 20/29 mice, compared to 3/20 mice injected with parasites grown with 10% rabbit blood, or 1/30 mice that received parasites grown with rabbit haemoglobin. The concentration of peanut lectin (PNA) required to agglutinate promastigotes was used as an index of… CONTINUE READING

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