Haemodynamic stability with midazolam-ketamine-sufentanil analgesia in cardiac surgical patients.

@article{Raza1989HaemodynamicSW,
  title={Haemodynamic stability with midazolam-ketamine-sufentanil analgesia in cardiac surgical patients.},
  author={S. Mahmood Raza and Rich Sw Masters and Elem{\'e}r K. Zsigmond},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={1989},
  volume={36 6},
  pages={617-23}
}
Although sufentanil in high doses may result in deep coma sufficient to conduct coronary-bypass surgery painlessly in patients, its side effects, e.g., bradycardia and hypotension, may lead to complications in some patients. Since ketamine causes central sympathetic stimulation, we attempted to counteract the vagomimetic effects of sufentanil by ketamine. Anaesthesia was induced in patients, (n = 15), for elective coronary artery-bypass surgery with 0.12 mg.kg-1 midazolam IV, followed by 1 mg… CONTINUE READING