Haemodynamic responses to 1.25 and 2 mg of terlipressin intravenously in man.

@article{Freeman1988HaemodynamicRT,
  title={Haemodynamic responses to 1.25 and 2 mg of terlipressin intravenously in man.},
  author={Jan G. Freeman and John Roger Barton and Christopher Oswold Record},
  journal={Alimentary pharmacology & therapeutics},
  year={1988},
  volume={2 4},
  pages={361-7}
}
The systemic and hepatic haemodynamic effects following terlipressin (Glypressin) administration were studied. Bolus intravenous injections of 1.25 and 2 mg significantly decreased wedged hepatic vein pressure gradient by 29% and 31%, respectively. With each dose there was a small increase in mean arterial blood pressure but after 1.25 mg of terlipressin, estimated hepatic blood flow fell by only 11% (not significant) compared to 24% after 2 mg, while the cardiac index fell by 12% compared to… CONTINUE READING