Haemodynamic changes and skeletal muscle oxygen tension during complete blood exchange with ultrapurified polymerized bovine haemoglobin

@article{Standl1997HaemodynamicCA,
  title={Haemodynamic changes and skeletal muscle oxygen tension during complete blood exchange with ultrapurified polymerized bovine haemoglobin},
  author={Thomas G Standl and Wolfram Reeker and G. Redmann and Eberhard F. Kochs and Christian Werner and Jochen Schulte am Esch},
  journal={Intensive Care Medicine},
  year={1997},
  volume={23},
  pages={865-872}
}
Objective: The study investigates the effect of continuous blood exchange with ultrapurified, polymerized bovine haemoglobin (UPBH) in comparison to hetastarch on haemodynamics, oxygen transport and skeletal muscle oxygen tension in a canine model. Design: Sixteen anaesthetized beagle dogs underwent haemodilution with lactated Ringer's to a starting haematocrit of 20 % followed by progressive blood exchange with 6 % hetastarch 200,000/0.5 (HES, group 1) or UPBH (haemoglobin 13 ± 1 g · dl−1… CONTINUE READING

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