Haemochromatosis

@article{Powell2016Haemochromatosis,
  title={Haemochromatosis},
  author={L. Powell and Rebecca Seckington and Y. Deugnier},
  journal={The Lancet},
  year={2016},
  volume={388},
  pages={706-716}
}
  • L. Powell, Rebecca Seckington, Y. Deugnier
  • Published 2016
  • Medicine
  • The Lancet
    • Haemochromatosis is now known to be an iron-storage disease with genetic heterogeneity but with a final common metabolic pathway resulting in inappropriately low production of the hormone hepcidin. This leads to increase in intestinal absorption and deposition of excessive amounts of iron in parenchymal cells which in turn results in eventual tissue damage and organ failure. A clinical enigma has been the variable clinical expression with some patients presenting with hepatic cirrhosis at a… CONTINUE READING
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