Haematopoietic stem cell transplantation for autoimmune diseases

  title={Haematopoietic stem cell transplantation for autoimmune diseases},
  author={J. Swart and Eveline M. Delemarre and F. Wijk and J. Boelens and J. Kuball and J. Laar and N. Wulffraat},
  journal={Nature Reviews Rheumatology},
  • J. Swart, Eveline M. Delemarre, +4 authors N. Wulffraat
  • Published 2017
  • Medicine
  • Nature Reviews Rheumatology
  • Autologous haematopoietic stem cell transplantation (HSCT) is the only treatment that is able to induce long-term, drug-free and symptom-free remission in several refractory autoimmune rheumatic diseases. Over 3,000 HSCT procedures for rheumatic and nonrheumatic severe autoimmune diseases have been performed worldwide. Specific conditioning regimens are currently used to eradicate the autoreactive immunological memory of patients. Although in vivo immune cell depletion with antithymocyte… CONTINUE READING
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