Haematological toxicity of cranio-spinal irradiation.

  title={Haematological toxicity of cranio-spinal irradiation.},
  author={Steven Jefferies and Balakrishnan Rajan and Susan W. Ashley and Daphne Traish and Michael Brada},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  volume={48 1},
BACKGROUND To assess the frequency and severity of myelosuppression due to cranio-spinal irradiation either alone or in combination with chemotherapy and to identify patients at high risk of haematological toxicity who may require supportive therapy. MATERIALS AND METHODS Between 1965 and 1994, 210 patients received cranio-spinal axis (CSA) radiotherapy as a component of treatment for primary CNS tumours at the Royal Marsden Hospital. Full blood counts (FBC) were obtained before, during and… CONTINUE READING


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