Habituation to pain: further support for a central component.

Abstract

Habituation to repetitive painful stimulation may represent an important protection mechanism against the development of chronic pain states. However, the exact neurobiological mechanisms of this phenomenon remain unclear. In this study we (i) explore the somatotopic specificity of pain attenuation over time and (ii) investigate the role of the endogenous… (More)
DOI: 10.1016/j.pain.2009.12.014

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