Habituation of arousal responses after intermittent hypercapnic hypoxia in piglets.

@article{Waters2005HabituationOA,
  title={Habituation of arousal responses after intermittent hypercapnic hypoxia in piglets.},
  author={Karen A Waters and Kellie D. Tinworth},
  journal={American journal of respiratory and critical care medicine},
  year={2005},
  volume={171 11},
  pages={
          1305-11
        }
}
RATIONALE Clinical studies have demonstrated arousal deficits in infants suffering obstructive sleep apnea, and some infant deaths have been attributed to such an arousal deficit. OBJECTIVES To evaluate whether arousal deficits can be induced by intermittent asphyxia during normal development. METHODS AND MEASUREMENTS Young piglets were exposed to intermittent hypercapnic hypoxia for 4 days from age 9.55 +/- 0.5 days. Arousal responses were compared between control animals and animals… CONTINUE READING
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