Habituation in rodents: a review of behavior, neurobiology, and genetics.

  title={Habituation in rodents: a review of behavior, neurobiology, and genetics.},
  author={Melanie P. Leussis and Valerie J. Bolivar},
  journal={Neuroscience and biobehavioral reviews},
  volume={30 7},
Habituation to a novel environment in rodents is commonly defined as a change in exploratory or locomotor activity over time (intrasession) or with repeated exposures (intersession). While numerous neuroactive substances are known to influence habituation, neurotransmitters that play particularly important roles are serotonin, acetylcholine, dopamine and glutamate. Although habituation is a complex process, studies over the past two decades have demonstrated that there is a genetic component… CONTINUE READING

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