HWGMWSY, an unanticipated polystyrene binding peptide from random phage display libraries.

@article{Vodnik2012HWGMWSYAU,
  title={HWGMWSY, an unanticipated polystyrene binding peptide from random phage display libraries.},
  author={Miha Vodnik and B. Strukelj and Mojca Lunder},
  journal={Analytical biochemistry},
  year={2012},
  volume={424 2},
  pages={83-6}
}
Phage display is a powerful technique for the discovery of peptide ligands that bind to various targets; however, ambiguous results often appear. Peptide HWGMWSY has been isolated repeatedly in our laboratory and by other research groups dealing with different protein and nonprotein targets, which led to a hypothesis that it may be a target-unrelated peptide interacting with polystyrene plastic surfaces. We compared binding properties and amplification rate of phage clone displaying the peptide… CONTINUE READING