HU binds and folds single-stranded DNA

  title={HU binds and folds single-stranded DNA},
  author={Dmitri Kamashev and Anna Balandina and Alexey K. Mazur and Paola B. Arimondo and Josette Rouviere-Yaniv},
  booktitle={Nucleic acids research},
The nucleoid-associated protein HU plays an important role in bacterial nucleoid organization and is involved in numerous processes including transposition, recombination and DNA repair. We show here that HU binds specifically DNA containing mismatched region longer than 3 bp as well as DNA bulges. HU binds single-stranded DNA (ssDNA) in a binding mode that… CONTINUE READING

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