HTLV envelopes and their receptor GLUT1, the ubiquitous glucose transporter: a new vision on HTLV infection?

@article{Manel2004HTLVEA,
  title={HTLV envelopes and their receptor GLUT1, the ubiquitous glucose transporter: a new vision on HTLV infection?},
  author={Nicolas Manel and Naomi Taylor and Sandrina Kinet and Felix J. Kim and Louise Swainson and Madakasira Lavanya and Jean-Luc Battini and Marc Sitbon},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2004},
  volume={9},
  pages={3218-41}
}
We identified the ubiquitous glucose transporter GLUT1 as a receptor for Deltaretroviruses HTLV-1 and HTLV-2 envelopes (Env), mediating viral binding and entry. Here, we review the context and key observations that led us to this finding: functional modules of HTLV SU are similar to those of Gammaretrovirus Env which use multimembrane-spanning nutrient… CONTINUE READING