HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation


The human T-lymphotropic virus type 1 (HTLV-1) is efficiently transmitted through cellular contacts. While the molecular mechanisms of viral cell-to-cell propagation have been extensively studied in vitro, those facilitating the encounter between infected and target cells remain unknown. In this study, we demonstrate that HTLV-1-infected CD4 T cells secrete… (More)
DOI: 10.1038/ncomms15890


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