HTLV-1 and Innate Immunity

@inproceedings{Journo2011HTLV1AI,
  title={HTLV-1 and Innate Immunity},
  author={Chlo{\'e} Journo and Renaud Mahieux},
  booktitle={Viruses},
  year={2011}
}
Innate immunity plays a critical role in the host response to a viral infection. The innate response has two main functions. First, it triggers effector mechanisms that restrict the infection. Second, it primes development of the adaptive response, which completes the elimination of the pathogen or of infected cells. In vivo, HTLV-1 infects T lymphocytes that participate in adaptive immunity but also monocytes and dendritic cells that are major players in innate immunity. Herein, we will review… CONTINUE READING
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