HTLV-1 Tax-induced NF-κB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity

@article{AzranShaish2008HTLV1TN,
  title={HTLV-1 Tax-induced NF-κB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity},
  author={Inbal Azran-Shaish and Yulia Tabakin-Fix and Mahmoud M Huleihel and Mary Bakhanashvili and M. Aboud},
  journal={Journal of Molecular Medicine},
  year={2008},
  volume={86},
  pages={799-814}
}
Nuclear factor kappa B (NF-κB) factors regulate a wide range of physiological and oncogenic processes. Normally, these factors are transiently activated by specific external signals which induce their dissociation from inhibitors of κB (IκB) and subsequent translocation to the nucleus where p65 links to the cyclic adenosine monophosphate response element… CONTINUE READING