HTLV-1 Specific CD8+ T Cell Function Augmented by Blockade of 2B4/CD48 Interaction in HTLV-1 Infection

Abstract

CD8+ T cell response is important in the response to viral infections; this response though is regulated by inhibitory receptors. Expression of inhibitory receptors has been positively correlated with CD8+ T cell exhaustion; the consequent effect of simultaneous blockade of these inhibitory receptors on CD8+ T cell response in viral infections have been… (More)
DOI: 10.1371/journal.pone.0087631

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