HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain?

@article{Heck2011HSP70ED,
  title={HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain?},
  author={Thiago Gomes Heck and Cinthia Maria Sch{\"o}ler and Paulo Ivo Homem de Bittencourt},
  journal={Cell biochemistry and function},
  year={2011},
  volume={29 3},
  pages={215-26}
}
Integrative physiology studies have shown that immune system and central nervous system interplay very closely towards behavioural modulation. Since the 70-kDa heat shock proteins (HSP70s), whose heavy expression during exercise is well documented in the skeletal muscle and other tissues, is also extremely well conserved in nature during all evolutionary periods of species, it is conceivable that HSP70s might participate of physiologic responses such as fatigue induced by some types of physical… CONTINUE READING
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