HSCs play a distinct role in different phases of oval cell-mediated liver regeneration.

@article{Chen2012HSCsPA,
  title={HSCs play a distinct role in different phases of oval cell-mediated liver regeneration.},
  author={Lin Chen and Wei Zhang and Qiao-dan Zhou and Hong-qiang Yang and Hui‐fang Liang and Bixiang Zhang and Xin Long and Xiaoping Chen},
  journal={Cell biochemistry and function},
  year={2012},
  volume={30 7},
  pages={588-96}
}
Hepatic stem cell niche plays an important role in hepatic oval cell-mediated liver regeneration. As a component of hepatic stem cell niche, the role of hepatic stellate cells (HSCs) in oval cell proliferation needs further studies. In the present study, we isolated HSCs from rats at indicated time point after partial hepatectomy (PH) in 2-acetylaminofluorene/PH oval cell proliferation model. Conditional medium (CM) from HSCs were collected to detect their effects on proliferation and the… CONTINUE READING

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