HPV16E6-Dependent c-Fos Expression Contributes to AP-1 Complex Formation in SiHa Cells

Abstract

To date, the major role of HPV16E6 in cancer has been considered to be its ability to inhibit the p53 tumor-suppressor protein, thereby thwarting p53-mediated cytotoxic responses to cellular stress signals. Here, we show that HPV16E6-dependent c-fos oncogenic protein expression contributes to AP-1 complex formation under oxidative stress in SiHa cells… (More)
DOI: 10.1155/2011/263216

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