HPV detection in primary intra-oral squamous cell carcinomas--commensal, aetiological agent or contamination?

@article{Boy2006HPVDI,
  title={HPV detection in primary intra-oral squamous cell carcinomas--commensal, aetiological agent or contamination?},
  author={Sonja Catharina Boy and Estrelita Janse Van Van Rensburg and Susan Engelbrecht and Leonora Dreyer and Marlene van Heerden and Willie van Heerden},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2006},
  volume={35 2},
  pages={86-90}
}
BACKGROUND High-risk human papilloma viruses (HPV) are reported to be significant independent risk factors for oral squamous cell carcinoma (OSCC). The prevalence of HPV in OSCC in a South African population sample was evaluated comparing three different HPV detection methods. METHODS Tumour and adjacent morphologically normal oral mucosa of 59 resections of primary OSCC were evaluated for the presence of HPV using real-time polymerase chain reaction (PCR), conventional in situ hybridization… CONTINUE READING