HPV Prophylactic Vaccination in Males Improves the Clearance of Semen Infection☆

@inproceedings{Foresta2015HPVPV,
  title={HPV Prophylactic Vaccination in Males Improves the Clearance of Semen Infection☆},
  author={C Foresta and Andrea Garolla and Saverio Giuseppe Parisi and Marco Ghezzi and Alessandro Bertoldo and Andrea Di Nisio and Luca De Toni},
  booktitle={EBioMedicine},
  year={2015}
}
BACKGROUND Semen represents a reservoir for human papillomavirus (HPV), rising concern in couples eligible for assisted reproduction techniques (ART). Humoral immunity against HPV is considered to protect from reinfection. We investigated the impact of vaccination on virus clearance in a cohort of infertile male patients showing HPV semen infection. METHODS 179 out of 619 infertile patients, showing HPV-DNA detection in semen by FISH analysis,were enrolled. Subjectswere split into 91 vaccine… CONTINUE READING
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