HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis.

@article{Ndiaye2014HPVDE,
  title={HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis.},
  author={Cathy Ndiaye and Marisa Mena and Laia Alemany and Marc Arbyn and Xavier Castellsagu{\'e} and Louise Laporte and Francesc Xavier Bosch and Silvia de Sanjos{\'e} and Helen Trottier},
  journal={The Lancet. Oncology},
  year={2014},
  volume={15 12},
  pages={1319-31}
}
BACKGROUND We aimed to provide updated information about the global estimates of attributable fraction and type distribution of human papillomavirus (HPV) in head and neck squamous cell carcinomas by doing a systematic review and meta-analysis. METHODS We did a literature search on PubMed to identify studies that used PCR for detection of HPV DNA in head and neck squamous cell carcinomas with information about HPV genotype distribution. We included studies that tested 20 or more biopsies per… CONTINUE READING
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