HPV 16 and cigarette smoking as risk factors for high-grade cervical intra-epithelial neoplasia.

@article{Ho1998HPV1A,
  title={HPV 16 and cigarette smoking as risk factors for high-grade cervical intra-epithelial neoplasia.},
  author={Gloria Y. F. Ho and Anna S Kadish and Robert D Burk and Jayasri Basu and Prabhudas R. Palan and M. Mikhail and S L Romney},
  journal={International journal of cancer},
  year={1998},
  volume={78 3},
  pages={281-5}
}
Although genital human papillomavirus (HPV) infection is well established as the etiologic agent for cervical intraepithelial neoplasia (CIN), little is known about the cofactors involved in the development of high-grade lesions or the progression of low-grade to high-grade lesions. In our study of HPV-infected women with CIN (163 CIN I, 51 CIN II and 44 CIN III), women with CIN II or III were compared with those with CIN I for risk factors associated with high-grade lesions. After controlling… CONTINUE READING
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Natural history of cervical human papillomavirus lesions does not substantiate the biologic relevance of the Bethesda system

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