HPTLC-Densitometric Analysis of Candesartan Cilexetil and Hydrochlorothiazide in Tablets

@inproceedings{Mehta2008HPTLCDensitometricAO,
  title={HPTLC-Densitometric Analysis of Candesartan Cilexetil and Hydrochlorothiazide in Tablets},
  author={Bipin H. Mehta and Sachin B. Morge},
  year={2008}
}
A simple, rapid and precise high-performance thin-layer chromatographic (HPTLC) method for analysis of candesartan cilexetil and hydrochlorothiazide in their tablet dosage forms has been developed and validated. Chromatography was performed on silica gel 60 GF 254 plates with acetone-chloroform-ethyl acetate-methanol 3:3:3:0.5 ( v/v ) as mobile phase. Detection was performed at 280 nm. The R F values were 0.27 for candesartan cilexetil and 0.45 for hydrochlorothiazide. Regression plots revealed… CONTINUE READING

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