HPLC-high resolution mass spectrometry in clinical laboratory?

@article{Jiwan2011HPLChighRM,
  title={HPLC-high resolution mass spectrometry in clinical laboratory?},
  author={Jean-Louis Habib Jiwan and P. Wallemacq and M. H{\'e}rent},
  journal={Clinical biochemistry},
  year={2011},
  volume={44 1},
  pages={
          136-47
        }
}
To date, GC-MS and LC-tandem MS techniques emerged quite frequently in laboratory medicine. However, high-resolution mass spectrometric (HRMS) analyzers remain almost ignored, even though in academic environment, they become more largely used. The main objective of this work is to present and illustrate with several applications, current high resolution mass spectrometric systems which could be useful for clinical applications. Among these systems are the Time-of-Flight (TOF) and Orbitrap… Expand

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