HPLC electrochemical detection of trace amines in human plasma and platelets and expression of mRNA transcripts of trace amine receptors in circulating leukocytes

@article{Dandrea2003HPLCED,
  title={HPLC electrochemical detection of trace amines in human plasma and platelets and expression of mRNA transcripts of trace amine receptors in circulating leukocytes},
  author={Giovanni D'andrea and Salvatore Terrazzino and D. Fortin and Angelo Farruggio and Luciano Rinaldi and Alberta Leon},
  journal={Neuroscience Letters},
  year={2003},
  volume={346},
  pages={89-92}
}
We evaluated, using a multi-channel electrochemical HPLC system, whether trace amines are detectable in plasma and platelets of healthy control subjects. To this end, levels of tyramine, octopamine and synephrine were assessed in samples obtained from eight males and eight females, age matched and free from drugs. In plasma, octopamine was detectable in all subjects, synephrine in 15 and tyramine in six out of 16 subjects. Likewise, detectable levels of octopamine together with synephrine were… Expand
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