HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma.

@article{Tang2001HPLCAO,
  title={HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma.},
  author={P. Tang and M. V. Miles and A. Degrauw and A. Hershey and A. Pesce},
  journal={Clinical chemistry},
  year={2001},
  volume={47 2},
  pages={
          256-65
        }
}
BACKGROUND The percentage of reduced coenzyme Q(10) (CoQ(10)H(2)) in total coenzyme Q(10) (TQ(10)) is decreased in plasma of patients with prematurity, hyperlipidemia, and liver disease. CoQ(10)H(2) is, however, easily oxidized and difficult to measure, and therefore reliable quantification of plasma CoQ(10)H(2) is of clinical importance. METHODS Venous blood was collected into evacuated tubes containing heparin, which were immediately placed on ice and promptly centrifuged at 4 degrees C… Expand
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