HPA axis reactivity in chronic pelvic pain: association with depression.

@article{Wingenfeld2009HPAAR,
  title={HPA axis reactivity in chronic pelvic pain: association with depression.},
  author={K Wingenfeld and Dirk H. Hellhammer and I. R. Schmidt and Dieter Wagner and Gunther Meinlschmidt and Christine M. Heim},
  journal={Journal of psychosomatic obstetrics and gynaecology},
  year={2009},
  volume={30 4},
  pages={282-6}
}
OBJECTIVES Chronic pelvic pain (CPP) is a frequent gynecological complaint. The pathophysiology of CPP is not fully understood. The aim of this study was to determine whether the presence of depressive symptoms is associated with hypothalamic-pituitary-adrenal (HPA) axis dysfunction in CPP. METHODS We measured neuroendocrine responses to a standardized social stress test and to a standard adrenocorticotropin (ACTH)(1-24) stimulation test in 18 patients with CPP, stratified based on the… CONTINUE READING