HPA-axis hyperactivity and mortality in psychotic depressive disorder: preliminary findings.

@article{Coryell2008HPAaxisHA,
  title={HPA-axis hyperactivity and mortality in psychotic depressive disorder: preliminary findings.},
  author={William H. Coryell and Jess Fiedorowicz and Mark Zimmerman and Elizabeth Young},
  journal={Psychoneuroendocrinology},
  year={2008},
  volume={33 5},
  pages={654-8}
}
BACKGROUND The excess mortality associated with depressive disorders has been most often attributed to risks for suicide but diverse findings indicate that depressive disorders also increase risks for cardiovascular (CV) mortality. Among the possible mediators is the hypothalamic-pituitary-adrenal (HPA)-axis hyperactivity that characterizes many cases of relatively severe depressive disorder and severity is characteristic of psychotic depressive disorder. METHODS The following describes a 17… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

The role of glucocorticoid action in the pathophysiology of the metabolic syndrome

  • M. Wang
  • Nutr. Metab. (Lond.)
  • 2005
2 Excerpts

Similar Papers

Loading similar papers…