HPA axis and cytokines dysregulation in schizophrenia: potential implications for the antipsychotic treatment.

@article{Altamura1999HPAAA,
  title={HPA axis and cytokines dysregulation in schizophrenia: potential implications for the antipsychotic treatment.},
  author={Alfredo Carlo Altamura and Francesco Boin and Michael Maes},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1999},
  volume={10 1},
  pages={1-4}
}
The authors discuss literature evidence on the possible dysfunctioning of HPA axis and the inflammatory response system (IRS) in schizophrenia in relation to a more comprehensive bio-pathogenetic hypothesis of the disorder and to the development of specific clinical patterns or 'core' schizophrenic symptoms, like those included in the so called negative/depressive dimension. The dysfunctions of HPA axis and IRS could be linked to some neurodevelopmental damage in relevant brain areas like… CONTINUE READING