HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation.

  title={HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation.},
  author={Maria Agnese Della Fazia and Marilena Castelli and Daniela Bartoli and Stefania Pieroni and Valentina Pettirossi and Danilo Piobbico and Mariapia Viola-Magni and Giuseppe Servillo},
  journal={Journal of cell science},
  volume={118 Pt 14},
The liver has the ability to autonomously regulate growth and mass. Following partial hepatectomy, hormones, growth factors, cytokines and their coupled signal transduction pathways have been implicated in hepatocyte proliferation. To understand the mechanisms responsible for the proliferative response, we studied liver regeneration by characterization of novel genes that are activated in residual hepatocytes. A regenerating liver cDNA library screening was performed with cDNA-subtracted probes… CONTINUE READING
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Cyclic AMP signaling in the liver coupling transcription to physiology and proliferation

  • G. Servillo, M. A. Della Fazia, P. Sassone-Corsi
  • The Liver : Biology and Pathobiology
  • 2001

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