HNF1 alpha gene coding regions mutations screening, in a Caucasian population clinically characterized as MODY from Argentina.


INTRODUCTION There are at least six subtypes of Maturity Onset Diabetes of the Young (MODY) with distinctive genetic causes. MODY 3 is caused by mutations in HNF1A gene, an insulin transcription factor, so mutations in this gene are associated with impaired insulin secretion. MODY 3 prevalence differs according to the population analyzed, but it is one of… (More)
DOI: 10.1016/j.diabres.2010.11.024