HMGNs, DNA repair and cancer.

Abstract

DNA lesions threaten the integrity of the genome and are a major factor in cancer formation and progression. Eukaryotic DNA is organized in nucleosome-based higher order structures, which form the chromatin fiber. In recent years, considerable knowledge has been gained on the importance of chromatin dynamics for the cellular response to DNA damage and for… (More)
DOI: 10.1016/j.bbagrm.2009.10.007

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