HMGI-C gene expression is not required for in vivo thyroid cell transformation.

@article{Scala2001HMGICGE,
  title={HMGI-C gene expression is not required for in vivo thyroid cell transformation.},
  author={Stefania Scala and G Portella and Donata Vitagliano and Catherine A. Ledent and Gennaro Chiappetta and Vincenzo Giancotti and J Dumont and Alfredo Fusco},
  journal={Carcinogenesis},
  year={2001},
  volume={22 2},
  pages={251-6}
}
We have previously demonstrated that HMGI proteins are required for the transformation of rat thyroid cells by v-mos and v-ras-Ki oncogenes. To determine whether HMGI proteins are also required for in vivo thyroid carcinogenesis, mice carrying a disrupted HMGI-C gene (pygmy mice) were either treated with radioactive iodine or crossed with transgenic mice… CONTINUE READING