HMGB1 level in cerebrospinal fluid as a complimentary biomarker for the diagnosis of tuberculous meningitis

Abstract

PURPOSE High mobility group box-1 (HMGB1) is a proinflammatory, DAMP protein that participates in many pathological conditions. In this study, we evaluated the usability of CSF HMGB1 as a biomarker for the diagnosis of tuberculous meningitis (TBM). METHODS A total of 59 TBM patients and 169 control patients were included in our study. CSF samples were… (More)
DOI: 10.1186/s40064-016-3478-5

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