HMGB1, a novel inflammatory cytokine.

  title={HMGB1, a novel inflammatory cytokine.},
  author={Shingo Yamada and Ikuro Maruyama},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={375 1-2},
High mobility group box 1 (HMGB1) exhibits unique biochemical functions as a biologically intrinsic requisite factor and as a toxin. As such, it is imperative to understand the mechanism by which these seemingly and diametrically opposed functions are exerted. To effectively discriminate these actions is important to accurately and precisely determine the concentration of HMGB1 in biological samples. Research in this fascinating field, however, has been lacking due to the absence of a simple… CONTINUE READING

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