HMGA1 mediates the activation of the CRYAB promoter by BRG1.

@article{Duncan2007HMGA1MT,
  title={HMGA1 mediates the activation of the CRYAB promoter by BRG1.},
  author={Beverly Duncan and Keji Zhao},
  journal={DNA and cell biology},
  year={2007},
  volume={26 10},
  pages={745-52}
}
alphaB-Crystallin (CRYAB) is a small heat-shock protein that is implicated in many cellular processes, such as transcription and differentiation, as well as pathologic process. It is expressed at high levels in vertebrate eye lens and at low levels in a variety of other cell types. We previously identified CRYAB as a target gene of the chromatin-remodeling SWI/SNF-like Brg or hBrm-associated factors (BAF) complexes. In this report, we identify a 30 bp DNA element required for mediating the… CONTINUE READING