HMGA1/HMGA2 protein expression and prognostic implications in gastric cancer.

@article{Jun2015HMGA1HMGA2PE,
  title={HMGA1/HMGA2 protein expression and prognostic implications in gastric cancer.},
  author={Kyong Hwa Jun and J Jung and Hyun-Joo Choi and E Y Shin and Hyung-min Chin},
  journal={International journal of surgery},
  year={2015},
  volume={24 Pt A},
  pages={39-44}
}
BACKGROUND The high mobility group A1 (HMGA1) and high mobility group A2 (HMGA2) proteins are architectural transcription factors that have been implicated in the pathogenesis and progression of multiple malignant tumors, including gastric cancer. The aim of this study was to explore the roles of HMGA1 and HMGA2 in gastric carcinogenesis. METHODS The expression of HMGA1 and HMGA2 was examined in 110 gastric adenocarcinomas, 29 gastric adenomas, and 30 normal controls. The results were… CONTINUE READING