HMG boxes of DSP1 protein interact with the rel homology domain of transcription factors.

@article{Decoville2000HMGBO,
  title={HMG boxes of DSP1 protein interact with the rel homology domain of transcription factors.},
  author={Martine Decoville and M J Giraud-Panis and Christine Mosrin-Huaman and Mei Chen Leng and Daniel Locker},
  journal={Nucleic acids research},
  year={2000},
  volume={28 2},
  pages={454-62}
}
Formation of the dorsoventral axis in Drosophila melanogaster is mediated through control of the expression of several genes by the morphogen Dorsal. In the ventral part of the embryo Dorsal activates twist and represses zen amongst others. Recently, several proteins have been shown to assist Dorsal in the repression of zen, one of which is DSP1, a HMG box protein that was isolated as a putative co-repressor of Dorsal. In this report we used a DSP1 null mutant to ascertain in vivo the… CONTINUE READING