HMG CoA reductase inhibitors are related to improved systemic endothelial function in coronary artery disease.

@article{Jrvisalo1999HMGCR,
  title={HMG CoA reductase inhibitors are related to improved systemic endothelial function in coronary artery disease.},
  author={Mikko J. J{\"a}rvisalo and Jyri O. Toikka and Tommi Juhani Vasankari and Jura Mikkola and Jorma Viikari and Jaakko J. Hartiala and Olli T. Raitakari},
  journal={Atherosclerosis},
  year={1999},
  volume={147 2},
  pages={237-42}
}
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase (statins) may enhance vascular endothelial function independent of their cholesterol lowering effect. To test this hypothesis, we surveyed two groups of patients (age 55+/-7, mean+/-SD) with coronary artery disease that were matched for age, blood pressure and serum lipid levels. Group 1 comprised 23 men without lipid-lowering medication and Group 2 included 22 patients with ongoing HMG CoA reductase inhibitor medication… CONTINUE READING

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