HMB supplementation: clinical and athletic performance-related effects and mechanisms of action

  title={HMB supplementation: clinical and athletic performance-related effects and mechanisms of action},
  author={N. Zanchi and F. Gerlinger-Romero and L. Guimar{\~a}es-Ferreira and M{\'a}rio Alves Siqueira Filho and Vitor Felitti and F. Lira and M. Seelaender and A. H. Lancha},
  journal={Amino Acids},
  • N. Zanchi, F. Gerlinger-Romero, +5 authors A. H. Lancha
  • Published 2010
  • Biology, Medicine
  • Amino Acids
  • Amino acids such as leucine and its metabolite α-ketoisocaproate (KIC), are returning to be the focus of studies, mainly because of their anti-catabolic properties, through inhibition of muscle proteolysis and enhancement of protein synthesis. It is clear that these effects may counteract catabolic conditions, as well as enhance skeletal muscle mass and strength in athletes. Moreover, beta-hydroxy-beta-methylbutyrate (HMB) has been shown to produce an important effect in reducing muscle damage… CONTINUE READING
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