HLA rs3129882 variant in Chinese Han patients with late-onset sporadic Parkinson disease.

@article{Guo2011HLARV,
  title={HLA rs3129882 variant in Chinese Han patients with late-onset sporadic Parkinson disease.},
  author={Yi Guo and Xiong Deng and Wen Zheng and Hongbo Xu and Zhi Zhong Song and Hui Liang and Jin Lei and Xuhong Jiang and Ziqiang Luo and Hao Deng},
  journal={Neuroscience letters},
  year={2011},
  volume={501 3},
  pages={185-7}
}
Recently, the rs3129882 variant in intron 1 of HLA-DRA was found to be associated with late-onset sporadic Parkinson disease (PD) in Americans of European ancestry. To evaluate whether the same variant is related to PD in Chinese population, we investigated late-onset sporadic PD patients of Chinese Han ethanicity in Mainland China. We found significant difference in genotypic and allele distribution between patients and control subjects (χ²)=6.446, p=0.040 for genotypic distribution; χ²=5.762… CONTINUE READING