HLA ligand profiles of primary renal cell carcinoma maintained in metastases

@article{Stickel2008HLALP,
  title={HLA ligand profiles of primary renal cell carcinoma maintained in metastases},
  author={Juliane Sarah Stickel and Andreas Oliver Weinzierl and Nina Hillen and Oliver Drews and Mathias M. Schuler and Joerg Hennenlotter and Dorothee Wernet and Claudia Anna M{\"u}ller and Arnulf Stenzl and Hans-Georg Rammensee and Stefan Stevanovi{\'c}},
  journal={Cancer Immunology, Immunotherapy},
  year={2008},
  volume={58},
  pages={1407-1417}
}
In recent years, several approaches have been taken in the peptide-based immunotherapy of metastatic renal cell carcinoma (RCC), although little is known about HLA presentation on metastases compared to primary tumor and normal tissue of RCC. In this study we compared primary tumor, normal tissue and metastases with the aim of identifying similarities and differences between these tissues. We performed this comparison for two RCC patients on the level of the HLA ligandome using mass… CONTINUE READING